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Western blot All lanes: ROCK2 antibody at 2ug/ml + Rat brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 161 kDa Observed band size: 161 kDa
Western blot All lanes: ROCK2 antibody at 2ug/ml + Rat brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 161 kDa Observed band size: 161 kDa
Western blot All lanes: ROCK2 antibody at 2ug/ml + Rat brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 161 kDa Observed band size: 161 kDa

ROCK2 Antibody

CSB-PA020059ESR1HU
Cusabio
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Rat
TargetROCK2
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Overview

  • Supplier
    Cusabio
  • Product Name
    ROCK2 Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID9475
  • Target name
    ROCK2
  • Target description
    Rho associated coiled-coil containing protein kinase 2
  • Target synonyms
    p164 ROCK-2; rho-associated protein kinase 2; rho-associated, coiled-coil-containing protein kinase II; ROCK-II
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75116
  • Protein Name
    Rho-associated protein kinase 2
  • Scientific Description
    Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca2+ sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203