Rodatristat ethyl

MedChem Express

Rodatristat ethyl [1673571-51-1]

9

1673571-51-1

98.04

C29H31ClF3N5O3

590.04

Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH) [1] [2] .

ClC1=CC(C2=CC=CC=C2)=C([C@@H](OC3=NC(N)=NC(N4CCC5(CN[C@H](C(OCC)=O)C5)CC4)=C3)C(F)(F)F)C=C1

-20°C,2°C to 8°C

12352200