Rogaratinib

Selleck Chemicals

Rogaratinib [1443530-05-9]

9

Research Use Only

...

Rogaratinib(BAY-1163877) is a highly potent and selective small molecule inhibitor of pan-FGFR kinase activity, which specifically inhibits FGFR1, 2, 3 and 4 with an IC50 values of 1.8 nM, <1 nM, 9.2 nM and 1.2 nM respectively. It demonstrates robust efficacy in cancers with altered FGFR mRNA expression.

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