ROR agonist-1 [2361528-74-5]

TargetMol Chemicals

ROR agonist-1

72

2361528-74-5

Chemical

Research Use Only

ROR agonist-1

C21H20F6N2O5S

526.45

ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), demonstrating inhibition of IL-17A production from human primary TH17 cells with a pIC50 of 7.5.

3 years

C(C(F)(F)F)(C(F)(F)F)(O)C1=CC=C(NC([C@H](NC(C)=O)C2=CC=C(S(CC)(=O)=O)C=C2)=O)C=C1

-20°C

12352200