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ROR2(ROR2/1911), CF640R conjugate, 0.1mg/mL [26628-22-8]

ROR2(ROR2/1911), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC401911
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetROR2
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Overview

  • Supplier
    Biotium
  • Product Name
    ROR2(ROR2/1911), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ROR2/1911
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID4920
  • Target name
    ROR2
  • Target description
    receptor tyrosine kinase like orphan receptor 2
  • Target synonyms
    BDB; BDB1; neurotrophic tyrosine kinase receptor-related 2; NTRKR2; tyrosine-protein kinase transmembrane receptor ROR2
  • Host
    Mouse
  • Isotype
    IgG
  • Protein IDQ01974
  • Protein Name
    Tyrosine-protein kinase transmembrane receptor ROR2
  • Scientific Description
    ROR2 (receptor tyrosine kinase-like orphan receptor 2), also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2), is a single pass transmembrane tyrosine-protein kinase receptor. It contains a cytoplasmic tyrosine kinase domain, distally located serine-threonine-rich domains, an extracellular immunoglobulin-like domain, a cysteine-rich domain and a kringle domain. ROR2 is important for skeletal and endocrine development and is required for cartilage and growth plate development. It promotes the differentiation of osteoblasts and plays an important role in the early formation of chondrocytes. ROR2 sequesters and associates with Dlxin-1 affecting the transcriptional function of Msx-2. ROR2 also interacts with canoncial Wnt-1 and Wnt-3, regulating their signaling pathways. Defects in ROR2 can result in the autosomal dominant skeletal disorder, brachydactyly type B1, or the autosomal recessive skeletal disorder, Robinow syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203