RORgamma/DHODH-IN-1

MedChem Express

RORgamma/DHODH-IN-1

9

Research Use Only

C23H13D2Cl2F4N3O2

514.30

RORgamma/DHODH-IN-1 (compound 1404), a deuterium labeled compound, is a dual RORgamma and DHODH inhibitor with IC50 values of 9.7 nM and 100 nM, repaectively. RORgamma/DHODH-IN-1 blocks the replication of SARS-CoV-2, HCMV, and non-enveloped DNA virus (HAdV5)[1].

ClC(C=CC=C1F)=C1C2=NOC(C3=C(N(C4=CC(Cl)=CC=C4)N=C3)C(F)(F)F)=C2C([2H])([2H])OC5CC5

12352200