RORgammat Inverse agonist 8 [2079892-79-6]
T12754
CAS Number2079892-79-6
Product group Chemicals
Molecular Weight475.59
Overview
- SupplierTargetMol Chemicals
- Product NameRORgammat Inverse agonist 8
- Delivery Days Customer72
- CAS Number2079892-79-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameRORgammat Inverse agonist 8
- Molecular FormulaC26H33N7O2
- Molecular Weight475.59
- Scientific DescriptionRORgammat Inverse agonist 8 is a potent, selective, orally bioavailable RORgammat inverse agonist (human RORgammat-LBD) with an IC50 of 19 nM.
- Shelf life instruction3 years
- SMILESC(C=1C=2N(C=C(NC(=O)C=3C=NC(C)=NC3)C1C)C=CN2)N4C[C@H](C)N(C(=O)C5CCCC5)CC4
- Storage Instruction-20°C
- UNSPSC12352200
References
- Pharmacological inhibition of RORgammat suppresses the Th17 pathway and alleviates arthritis in vivo. Guendisch U et al., 2017, PLoS OneRead more