Roscovitine [186692-46-6]
R5774
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameRoscovitine [186692-46-6]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatSoluble in DMSO or chloroform.
- Scientific DescriptionCDK inhibitor, L-type Ca2+ channel blocker.; Seliciclib, CYC202
- Storage Instruction-20°C
- UNSPSC12352200
References
- Leitch AE, Haslett C, Rossi AG. Cyclin-dependent kinase inhibitor drugs as potential novel anti-inflammatory and pro-resolution agents. Br J Pharmacol. 2009 Oct;158(4):1004-16. PMID: 19775281. Yarotskyy V, Elmslie KS. Roscovitine, a cyclin-dependent kinase inhibitor, affects several gating mechanisms to inhibit cardiac L-type (Ca(V)1.2) calcium channels. Br J Pharmacol. 2007 Oct;152(3):386-95. PMID: 17700718. Lacrima K, Rinaldi A, Vignati S, et al. Cyclin-dependent kinase inhibitor seliciclib shows in vitro activity in diffuse large B-cell lymphomas. Leuk Lymphoma. 2007 Jan;48(1):158-67. PMID: 17325859.