Rosiglitazone [122320-73-4]
R5773
Estimated Purity≥99%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameRosiglitazone [122320-73-4]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥99%
- FormatSoluble in ethanol and in buffered aqueous solutions (pH of 2.3).
- Scientific DescriptionThiazolidinedione; PPARgamma agonist.; BRL-49653
- Storage InstructionAmbient
- UNSPSC12352200
References
- Rui M, Huang Z, Liu Y, et al. Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia inducible factor 1alfa and insulin like growth factor 1 mRNA expression. Mol Med Rep. 2014 Jul 22. [Epub ahead of print]. PMID: 25050627. Mingfeng D, Xiaodong M, Yue L, et al. Effects of PPAR-gamma Agonist Treatment on LPS-Induced Mastitis in Rats. Inflammation. 2014 May 18. [Epub ahead of print]. PMID: 24839089. Liu Y, Tian XY, Huang Y, et al. Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension via Differential Regulation of ET-1 Receptors. PPAR Res. 2014;2014:374075. PMID: 24701204. He H, Tao H, Xiong H, et al. Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor gamma-independent mitochondrial oxidative stress in mouse hearts. Toxicol Sci. 2014 Apr;138(2):468-81. PMID: 24449420. Hou X, Zhang Y, Shen YH, et al. PPAR-gamma activation by rosiglitazone suppresses angiotensin II-mediated proliferation and phenotypictransition in cardiac fibroblasts via inhibition of activation of activator protein 1. Eur J Pharmacol. 2013 Sep 5;715(1-3):196-203. PMID: 23791613.