RP-001 (hydrochloride) [1781880-34-9]

MedChem Express

RP-001 (hydrochloride) [1781880-34-9]

10

1781880-34-9

Research Use Only

98.8

C24H25ClN4O4

468.93

RP-001 hydrochloride is a picomolar short-acting S1P1 (EDG1) selective agonist, with an EC50 of 9 pM. RP-00 hydrochloride induces internalization and polyubiquitination of S1P1. RP-001 hydrochloride has little activity on S1P2-S1P4 and only moderate affinity for S1P5[1].

O=C(O)CCNC1CCC2=C1C=CC=C2C3=NOC(C4=CC=C(OC(C)C)C(C#N)=C4)=N3.Cl

-20°C

12352200