RP-6685

MedChem Express

RP-6685

10

99.96

C22H14F7N5O

497.37

RP-6685 is a potent, selective and orally active DNA polymerase theta (Poltheta) inhibitor with an IC 50 value of 5.8 nM (PicoGreen assay). RP-6685 shows antitumor efficacy in mouse tumor xenograft model [1] . RP-6685 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(N(CC#CC1=NN=C(N)C=C1)C2=CC=C(F)C=C2)CC3=NC=C(C(F)(F)F)C=C3C(F)(F)F

-20°C,2°C to 8°C

12352200