RP 72540

MedChem Express

RP 72540

9

C28H30N4O6

518.56

RP 72540 is a selective CCK-B receptor antagonist, with IC 50 values of 2.4, 1.2, and 3.8 nM for CCK-B receptors in the guinea pig cerebral cortex, rat cerebral cortex, and mouse brain, respectively. RP 72540 effectively inhibits CCK-8 -induced neuronal firing and dose-dependently inhibits gastric acid secretion, making it potentially valuable in studies of acid secretion. RP 72540 is an important tool for investigating the physiological functions of CCK B receptors [1] .

O=C(N(C1=CC=CC(OC)=C1)CC(N(C)C2=CC=CC=C2)=O)CNC(NC3=CC=CC(C(C(O)=O)C)=C3)=O

12352200