RP101075 [1306760-73-5]

MedChem Express

RP101075 [1306760-73-5]

10

1306760-73-5

Research Use Only

99.19

C21H20N4O2

360.41

RP101075, an active metabolite of Ozanimod, is a potent, orally active S1PR (sphingosine-1-phosphate receptor 1) agonist, with an EC50 of 0.27 nM. RP101075 displays >100-fold selectivity over S1PR5 (EC50=5.9 nM) and >10000-fold over S1PR 2, 3, and 4. RP101075 displays superior cardiovascular safety profile[1].

N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4N)=NO2)=CC=C1OC(C)C

-20°C,2°C to 8°C

12131703