RPE65 Antibody, Biotin conjugated

Cusabio

RPE65 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

RPE65

retinoid isomerohydrolase RPE65

all-trans-retinyl-palmitate hydrolase; BCO family, member 3; BCO3; LCA2; lutein isomerase; meso-zeaxanthin isomerase; mRPE65; p63; RBP-binding membrane protein; rd12; retinal pigment epithelium specific protein 65; retinal pigment epithelium-specific 65 kDa protein; retinal pigment epithelium-specific protein 65kDa; retinitis pigmentosa 20 (autosomal recessive); retinoid isomerohydrolase; retinol isomerase; RP20; RPE65, retinoid isomerohydrolase; sRPE65

Rabbit

IgG

Retinoid isomerohydrolase

Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Human

-20°C or -80°C

12352203