RRAD Polyclonal Antibody
RD78747A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRRAD
Overview
- SupplierReddot Biotech
- Product NameRRAD Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID6236
- Target nameRRAD
- Target descriptionRRAD, Ras related glycolysis inhibitor and calcium channel regulator
- Target synonymsGTP-binding protein RAD; RAD; RAD1; RAS (RAD and GEM) like GTP binding 3; ras associated with diabetes; Ras-related associated with diabetes; REM3; RRAD, Ras related glycolysis inihibitor and calcium channel regulator
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203