(R,R,S)-GAT107

MedChem Express

(R,R,S)-GAT107

9

Research Use Only

C18H17BrN2O2S

405.31

(R,R,S)-GAT107 is a fully agonistic positive modulator of alpha7 nicotinic receptors with significant biological activity. Its activity is entirely present in its (+)-isomer 1b, while (-)-isomer 1a does not affect its activity when used together. Studies have shown that (R,R,S)-GAT107 is the most potent ago-PAM for alpha7 nicotinic receptors currently known and has the potential for further in vivo evaluation[1].

NS(=O)(C1=CC=C2N[C@@H](C3=CC=C(C=C3)Br)[C@](CC=C4)([H])[C@]4([H])C2=C1)=O

12352200