Bio-Connect

RS17

HY-P10420
MedChem Express
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RS17
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    99.82
  • Scientific Description
    RS17 is an anti-tumor peptide designed to bind specifically to the CD47 molecule and block the interaction between CD47 and its ligand, SIRPalpha, on the surface membrane of macrophages. The main regulatory mechanism of RS17 is to prevent CD47 from transmitting selective phagocytosis signals to SIRPalpha by binding to CD47 , so that macrophages do not recognize tumor cells as their own tissue, but phagocytose them as foreign substances, thereby inhibiting immune escape of tumor cells. RS17 can be used to study the mechanism of anti-tumor response and immune escape [1] .
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352202