RSM-932A

MedChem Express

RSM-932A [850807-63-5]

10

850807-63-5

98.44

C46H38Br2Cl2N4

877.53

RSM-932A (TCD-717) is a specific ChoKalpha inhibitor with IC 50 s of 1 and 33 microM for human recombinant ChoKalpha and ChoKbeta enzymes, respectively. RSM-932A acts as the first in humans compound targeting ChoKalpha. RSM-932A is potent in vitro anti-proliferative and in vivo anti-tumoral activity against human xenografts in mice, showing high efficacy with low toxicity profiles [1] [2] [3] .

CN(C1=C2C=CC=CC2=[N+](CC3=CC=C(C4=CC=C(C[N+]5=C6C=CC=CC6=C(N(C7=CC=C(Cl)C=C7)C)C=C5)C=C4)C=C3)C=C1)C8=CC=C(Cl)C=C8.[Br-].[Br-]

2°C to 8°C

12352200