RSPO1 Polyclonal Antibody

Reddot Biotech

RSPO1 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

RSPO1

R-spondin 1

CRISTIN3; roof plate-specific spondin-1; RSPO; R-spondin homolog; R-spondin-1

Rabbit

IgG

This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.

Human, Mouse, Rat

-20°C

12352203