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ProductsBack/RSPO3 Antibody, Biotin conjugated

RSPO3 Antibody, Biotin conjugated

Research Use Only
CSB-PA887154LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetRSPO3
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Cusabio
  • Product Name
    RSPO3 Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID84870
  • Target name
    RSPO3
  • Target description
    R-spondin 3
  • Target synonyms
    CRISTIN1; protein with TSP type-1 repeat; PWTSR; roof plate-specific spondin-3; R-spondin 3 homolog; R-spondin-3; thrombospondin type-1 domain-containing protein 2; thrombospondin, type I, domain containing 2; THSD2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9BXY4
  • Protein Name
    R-spondin-3
  • Scientific Description
    Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203