RSV L-protein-IN-5 [851658-28-1]

TargetMol Chemicals

RSV L-protein-IN-5 [851658-28-1]

16

Chemical

Research Use Only

RSV L-protein-IN-5

C31H36N6O4

556.66

RSV L-protein-IN-5 (Compound E) serves as a potent inhibitor of the Respiratory Syncytial Virus (RSV), with an EC50 value of 0.1 microM. It targets RSV polymerase with an IC50 of 0.66 microM and impedes RSV mRNA synthesis through the inhibition of transcript guanylation. The compound demonstrates moderate cytotoxicity, with a CC50 of 10.7 microM in HEp-2 cells, and effectively reduces viral titers in mouse models of RSV infection [1].

3 years

O=C1C=2C3=C(N=C(N3)C=4N=C(C)C=CC4)C(N)=CC2C(C)(C)C(=O)N1CCCNCCC5=CC(OC)=C(OC)C=C5

-20°C

51202000