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RSV/IAV-IN-3

Research Use Only
HY-143494
MedChem Express
Molecular Weight435.33
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RSV/IAV-IN-3
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C19H19BrN2O3S
  • Molecular Weight
    435.33
  • Scientific Description
    RSV/IAV-IN-3 (compound 14i) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza A virus (IAV) with EC50 values of 2.92 microM and 1.90 microM,respectively. RSV/IAV-IN-3 has antiviral effect against H1N1 and H3N2 with EC50 values of 3.25 microM and 1.50 microM in MDCK cells, respectively. RSV/IAV-IN-3 significantly inhibits the activity of luciferase in a dose-dependent manner, with an EC50 of 3.89 microM. RSV/IAV-IN-3 inhibits IAV infectivity and RdRp activity. RSV/IAV-IN-3 inhibits IAV and RSV replication at the post-entry stage[1].
  • SMILES
    O=C(NC1=CC=CC=C1OCC)CSC2=CNC3=C2C=CC(OC)=C3Br
  • UNSPSC
    12352200