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RTI-7470-44

HY-147319
MedChem Express
Estimated Purity99.85
DownloadMSDS
Product group Chemicals
Molecular Weight449.84
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RTI-7470-44
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    99.85
  • Molecular Formula
    C19H11ClF3N5OS
  • Molecular Weight
    449.84
  • Scientific Description
    RTI-7470-44 is a potent, selective and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist with an IC 50 value of 8.4 nM and a K i value of 0.3 nM. RTI-7470-44 has moderate metabolic stability, and a favorable preliminary off-target profile. RTI-7470-44 can increase the spontaneous firing rate of mouse ventral tegmental area (VTA) dopaminergic neurons. RTI-7470-44 can be used for researching schizophrenia, agent addiction, and Parkinsons disease (PD) [1] .
  • SMILES
    N#CC1=C(SCC(NC2=NC=CC=N2)=O)N=C(C3=CC=C(Cl)C=C3)C=C1C(F)(F)F
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200