Ruboxistaurin [169939-94-0]

MedChem Express

Ruboxistaurin [169939-94-0]

5

169939-94-0

Research Use Only

99.90

C28H28N4O3

468.55

Ruboxistaurin (LY333531) is an orally active, selective PKC beta inhibitor (Ki=2 nM). Ruboxistaurin exhibits ATP dependent competitive inhibition of PKC beta I with an IC50 of 4.7 nM. Ruboxistaurin inhibits PKC beta II with an IC50 of 5.9 nM[1][2].

O=C1NC(C(C2=CN(C3=CC=CC=C32)CCO[C@H](CN(C)C)CC4)=C1C5=CN4C6=CC=CC=C56)=O

-20°C,2°C to 8°C

12352200