Ruboxistaurin-d6 (hydrochloride)

MedChem Express

Ruboxistaurin-d6 (hydrochloride) [1794767-04-6]

10

1794767-04-6

Research Use Only

C28H23D6ClN4O3

511.04

Ruboxistaurin-d 6 (hydrochloride) is the deuterium labeled Ruboxistaurin hydrochloride. Ruboxistaurin (LY333531) hydrochloride is an orally active, selective PKC beta inhibitor (Ki=2 nM). Ruboxistaurin hydrochloride exhibits ATP dependent competitive inhibition of PKC beta I with an IC50 of 4.7 nM. Ruboxistaurin hydrochloride inhibits PKC beta II with an IC50 of 5.9 nM[1][2].

O=C1C2=C(C=3C=4C(N(C3)CCO[C@H](CN(C([2H])([2H])[2H])C([2H])([2H])[2H])CCN5C=C2C=6C5=CC=CC6)=CC=CC4)C(=O)N1.Cl

12352200