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RUNX1/ETO tetramerization-IN-1

Research Use Only
HY-151411
MedChem Express
Molecular Weight342.3
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RUNX1/ETO tetramerization-IN-1
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C18H14O7
  • Molecular Weight
    342.3
  • Scientific Description
    RUNX1/ETO tetramerization-IN-1 is a small-molecule inhibitor of RUNX1/ETO tetramerization, exhibits anti-leukemic effect. RUNX1/ETO tetramerization-IN-1 specifically targets to NHR2 of RUNX1/ETO (EC50=0.25 microM), restores gene expression down-regulated by RUNX1/ETO. RUNX1/ETO tetramerization-IN-1 inhibits the proliferation of RUNX1/ETO-depending SKNO-1 cells, and reduces the RUNX1/ETO-related tumor growth in a mouse model.
  • SMILES
    O=C(C(CC(C1=CC=C2OCOC2=C1)=O)C3=CC=C4OCOC4=C3)O
  • Storage Instruction
    See Manual
  • UNSPSC
    12352200