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Rutaecarpine [84-26-4]

Research Use Only
R8178
LKT Laboratories
Estimated Purity≥98%
Product group Chemicals
€ 398,00
25 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Rutaecarpine [84-26-4]
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Estimated Purity
    ≥98%
  • Format
    Soluble in alcohol, benzene, chloroform and ether. Practically insoluble in water.
  • Scientific Description
    Indoloquinazoline alkaloid found in Evodia; COX-2 inhibitor.; Rutecarpine
  • Storage Instruction
    4°C
  • UNSPSC
    12352200

References

  • Xu Y, Liu Q, Xu Y, et al. Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through up-regulating ABCA1 and SR-BI within RCT. J Lipid Res. 2014 Jun 7. [Epub ahead of print]. PMID: 24908654. Chen YC, Zeng XY, He Y, et al. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression. ACS Chem Biol. 2013 Oct 18;8(10):2301-11. PMID: 23962138. Bao MH, Dai W, Li YJ, et al. Rutaecarpine prevents hypoxia-reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases. Can J Physiol Pharmacol. 2011 Mar;89(3):177-86. PMID: 21423291. Kim SJ, Lee SJ, Lee S, et al. Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochem Biophys Res Commun. 2009 Nov 20;389(3):437-42. PMID: 19732749. Yu PL, Chao HL, Wang SW, et al. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J Cell Biochem. 2009 Oct 1;108(2):469-75. PMID: 19639602. Sheu JR, Hung WC, Lee YM, et al. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol. 1996 Dec 30;318(2-3):469-75. PMID: 9016940.