Rutaecarpine, synthetic [84-26-4]
R8179
Estimated Purity≥98%
Product group Chemicals
Overview
- SupplierLKT Laboratories
- Product NameRutaecarpine, synthetic [84-26-4]
- Delivery Days Customer7
- CertificationResearch Use Only
- Estimated Purity≥98%
- FormatSoluble in alcohol, benzene, chloroform and ether. Practically insoluble in water.
- Scientific DescriptionFound in Evodia rutaecarpa; potential cAMP, 3bèta-HSD, 11bèta-hydroxylase inhibitor.; Rutecarpine
- Storage Instruction4°C
- UNSPSC12352200
References
- Xu Y, Liu Q, Xu Y, et al. Rutaecarpine suppresses atherosclerosis in ApoE-/- mice through up-regulating ABCA1 and SR-BI within RCT. J Lipid Res. 2014 Jun 7. [Epub ahead of print]. PMID: 24908654. Chen YC, Zeng XY, He Y, et al. Rutaecarpine analogues reduce lipid accumulation in adipocytes via inhibiting adipogenesis/lipogenesis with AMPK activation and UPR suppression. ACS Chem Biol. 2013 Oct 18;8(10):2301-11. PMID: 23962138. Bao MH, Dai W, Li YJ, et al. Rutaecarpine prevents hypoxia-reoxygenation-induced myocardial cell apoptosis via inhibition of NADPH oxidases. Can J Physiol Pharmacol. 2011 Mar;89(3):177-86. PMID: 21423291. Kim SJ, Lee SJ, Lee S, et al. Rutecarpine ameliorates bodyweight gain through the inhibition of orexigenic neuropeptides NPY and AgRP in mice. Biochem Biophys Res Commun. 2009 Nov 20;389(3):437-42. PMID: 19732749. Yu PL, Chao HL, Wang SW, et al. Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats. J Cell Biochem. 2009 Oct 1;108(2):469-75. PMID: 19639602. Sheu JR, Hung WC, Lee YM, et al. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol. 1996 Dec 30;318(2-3):469-75. PMID: 9016940.