Bio-Connect

Ruzasvir

HY-101663
MedChem Express
Molecular Weight947.09
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ruzasvir
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Molecular Formula
    C49H55FN10O7S
  • Molecular Weight
    947.09
  • Scientific Description
    Ruzasvir (MK-8408) is an orally active inhibitor for genotypic HCV nonstructural protein 5A (NS5A), which inhibits the replication of NS5A mutants GT1a, GT1a L31V, GT1a Y93H, GT2b, GT3a and GT4a with EC 90 ranging from 0.003 to 0.067 nM. Ruzasvir exhibits good pharmacokinetic characters in rhesus monkey model [1] .
  • SMILES
    FC1=C2C3=CC4=CC(C5=CN=C([C@H](CCC6)N6C([C@H](C(C)C)NC(OC)=O)=O)N5)=CC=C4N3[C@H](C7=CN=C(C8CC8)S7)OC2=CC(C9=CN=C([C@H](CCC%10)N%10C([C@H](C(C)C)NC(OC)=O)=O)N9)=C1
  • UNSPSC
    12352200