S-312-d

MedChem Express

S-312-d

9

Research Use Only

C20H22N2O4S

386.46

S-312-d (S-(+)-S-312-d) is a calcium channel blocker with the activity of protecting the kidney from ischemic acute renal failure. S-312-d (0.01-0.1mg/kg b.wt. iv) administered before ischemia has a dose-dependent protective effect on ischemia-induced renal damage, improves the survival rate of ischemic rats, and reduces renal cortical edema and the increase in renal tissue calcium content.

CC(CC1=CSC2=C1[C@H](C(C(OC)=O)=C(N2)C)C3=CC([N+]([O-])=O)=CC=C3)C

12352200