(S)-CPP (sodium)

MedChem Express

(S)-CPP (sodium)

9

Research Use Only

C9H8ClNaO2

206.60

(S)-CPP sodium serves as an inhibitor of the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S)-CPP (with an IC50 of 6.3 microM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.

O=C(O[Na])[C@@H](Cl)CC1=CC=CC=C1

12352200