(S)-LY-3381916

MedChem Express

(S)-LY-3381916 [2166616-76-6]

10

2166616-76-6

Research Use Only

99.06

C23H25FN2O3

396.45

(S)-LY-3381916 ((S)-IDO1-IN-5; Example 1B) is an active S-isomer of LY-3381916. (S)-LY-3381916 binds to IDOL with an IC 50 value less than 1.5 micromicro [1] . LY-3381916 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1 [2] .

O=C(N[C@H](C1=CC2=C(N(C(C3CCOCC3)=O)CC2)C=C1)C)C4=CC=C(F)C=C4

-20°C,2°C to 8°C

12352200