(S)-Sitagliptin (phosphate) [823817-58-9]

MedChem Express

(S)-Sitagliptin (phosphate) [823817-58-9]

10

823817-58-9

Research Use Only

C16H18F6N5O5P

505.31

(S)-Sitagliptin phosphate is the less active S-enantiomer of Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts[1].

O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@@H](N)CC3=CC(F)=C(F)C=C3F.O=P(O)(O)O

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