S07-2010

MedChem Express

S07-2010

10

Research Use Only

99.79

C19H21N3O3S

371.45

S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 microM for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells[1].

O=C1CCCC2=CC(C(CSC3=NC(CCC)=CC(N3)=O)=O)=CC=C2N1

2°C to 8°C,-20°C

12352200