S100A9 + Calprotectin (S100A8/A9 Complex)(MAC3157R), CF594 conjugate, 0.1mg/mL [26628-22-8]

Biotium

S100A9 + Calprotectin (S100A8/A9 Complex)(MAC3157R), CF594 conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

MAC3157R

0.1 mg/ml

Other Conjugate

S100A8

S100 calcium binding protein A8

60B8AG; CAGA; calgranulin A; calprotectin L1L subunit; CFAG; CGLA; CP-10; cystic fibrosis antigen; L1Ag; leukocyte L1 complex light chain; MA387; MIF; migration inhibitory factor-related protein 8; MRP8; NIF; P8; protein S100-A8; S100-A8; urinary stone protein band A

Rabbit

IgG

Protein S100-A8

Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12 kDa alpha chain and a 14 kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffers cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhanss cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Canine, Equine, Feline, Guinea Pig, Goat, Human, Monkey, Mouse, Porcine, Primate, Rabbit, Rat

2°C to 8°C

12352203