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CgoaEGY7KmCELpYaAAAAAMzNccg050.png
CgoaEGY7KmCELpYaAAAAAMzNccg050.png
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S130

T12819
TargetMol Chemicals
CAS Number1160852-22-1
Product group Chemicals
Molecular Weight387.47
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    S130
  • Delivery Days Customer
    72
  • CAS Number
    1160852-22-1
  • Category Supplier
    Chemical
  • Chemical Name
    S130
  • Molecular Formula
    C24H25N3O2
  • Molecular Weight
    387.47
  • Scientific Description
    S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 uM).It suppresses autophagy flux.
  • Shelf life instruction
    3 years
  • SMILES
    C(NCCCN(CC)CC)(=O)C=1C=2C3=C(C=4C(C(=O)C3=NC1)=CC=CC4)C=CC2
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Fu Y, et al. Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo. Autophagy. 2018 Sep 20:1-17.
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