More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/S14161 [883046-50-2]
Chemical Structure
Chemical Structure
Chemical Structure

S14161 [883046-50-2]

Research Use Only
AG-CR1-3516
AdipoGen Life Sciences
CAS Number883046-50-2
DownloadMSDS
Product group Chemicals
Estimated Purity>99%
Molecular Weight315.3
Price on request
Packing Size
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    S14161 [883046-50-2]
  • Delivery Days Customer
    10
  • CAS Number
    883046-50-2
  • Certification
    Research Use Only
  • Estimated Purity
    >99%
  • Molecular Formula
    C17H14FNO4
  • Molecular Weight
    315.3
  • Scientific Description
    Chemical. CAS: 883046-50-2. Formula: C17H14FNO4. MW: 315.3. Potent antileukemia and antimyeloma compound. Apoptosis inducer. Delays tumor growth. Cyclin D2 promoter transactivation inhibitor. Inhibitor of pan-Class I PI3K isoforms. - Potent antileukemia and antimyeloma compound [1]. Apoptosis inducer [1]. Delays tumor growth [1]. Cyclin D2 promoter transactivation inhibitor [1]. Inhibitor of pan-Class I PI3K isoforms [1,2].
  • SMILES
    CCOC1=C2OC(C3=CC=C(F)C=C3)C(=CC2=CC=C1)[N+]([O-])=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway: X. Mao, et al.; Blood 117, 1986 (2011)
  • Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization: K. Han, et al.; J. Hematol. Oncol. 7, 1756 (2014)