SA-PA

TargetMol Chemicals

SA-PA

999

Chemical

Research Use Only

SA-PA

C40H32ClF3N10O8

873.19

SA-PA, a self-assembled intracellular PROTAC leveraging azide-alkyne click chemistry, selectively degrades VEGFR-2, PDGFR-beta, and EphB4 proteins within U87 cells. In the presence of endogenous copper in tumor tissues, SA-PA undergoes in situ conversion to active PROTAC through a click reaction [1].

3 years

-20°C

12352200