SAFB (C) Antibody, Rabbit Polyclonal

Biorbyt

SAFB antibody

16

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SAFB.

Western Blot

WB:1:1000-1:3000 WB

Research Use Only

Polyclonal

100 ug/ml

Unconjugated

SAFB

scaffold attachment factor B

glutathione S-transferase fusion protein; HAP; heat-shock protein (HSP27) estrogen response element and TATA box-binding protein; HET; Hsp27 ERE-TATA binding protein; HSP27 ERE-TATA-binding protein; HSP27 estrogen response element-TATA box-binding protein; SAB-B1; SAF-B; SAFB1; SAF-B1; scaffold attachment factor B1

Rabbit

Scaffold attachment factor B1

Rabbit polyclonal to SAFB. Scaffold attachment factor B (SAFB) is a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). SAFB is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. SAFB is thought to serve as a molecular base to assemble a transcriptosome complex in the vicinity of actively transcribed genes. SAFB is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene

Human

-20°C

12352203