Safinamide (mesylate)
HY-70057A
Overview
- SupplierMedChem Express
- Product NameSafinamide (mesylate) [202825-46-5]
- Delivery Days Customer5
- CAS Number202825-46-5
- CertificationResearch Use Only
- Estimated Purity99.87
- Molecular FormulaC18H23FN2O5S
- Molecular Weight398.45
- Scientific DescriptionSafinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor ( IC 50 =0.098 microM) over MAO-A (IC 50 =580 nM) [1] . Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized ( IC 50 =8?microM) than at resting ( IC 50 =262?microM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al [2] [3] .
- SMILESC[C@H](NCC1=CC=C(OCC2=CC=CC(F)=C2)C=C1)C(N)=O.CS(=O)(O)=O
- Storage Instruction2°C to 8°C
- UNSPSC12352200