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Safinamide (mesylate)

HY-70057A
MedChem Express
CAS Number202825-46-5
Product group Chemicals
Estimated Purity99.87
Molecular Weight398.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Safinamide (mesylate) [202825-46-5]
  • Delivery Days Customer
    5
  • CAS Number
    202825-46-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.87
  • Molecular Formula
    C18H23FN2O5S
  • Molecular Weight
    398.45
  • Scientific Description
    Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor ( IC 50 =0.098 microM) over MAO-A (IC 50 =580 nM) [1] . Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized ( IC 50 =8?microM) than at resting ( IC 50 =262?microM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al [2] [3] .
  • SMILES
    C[C@H](NCC1=CC=C(OCC2=CC=CC(F)=C2)C=C1)C(N)=O.CS(=O)(O)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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