Safinamide (mesylate) [202825-46-5]

MedChem Express

Safinamide (mesylate) [202825-46-5]

5

202825-46-5

Research Use Only

99.87

C18H23FN2O5S

398.45

Safinamide (FCE 26743; EMD 1195686) mesylate is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 microM) over MAO-A (IC50=580 nM)[1]. Safinamide mesylate also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8?microM) than at resting (IC50=262?microM) potentials. Safinamide mesylate has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke et.al[2][3].

C[C@H](NCC1=CC=C(OCC2=CC=CC(F)=C2)C=C1)C(N)=O.CS(=O)(O)=O

2°C to 8°C

12352200