Safotibant

MedChem Express

Safotibant [633698-99-4]

5

633698-99-4

C25H34N4O5S

502.63

Safotibant (LF22-0542) is a selective antagonist for kinin B1 receptor ( BKB1R ), with K i of 0.35 and 6.5 nM, for human and mouse BKB1R, respectively. Safotibant exhibits analgesic and anti-inflammatory property in mice model [1] [2] .

O=C(COCCN(S(=O)(C1=C(C)C=C(OC)C=C1C)=O)C)N(CC2=CC=C(C3=NCCN3)C=C2)C

12352200