SAG dihydrochloride [2702366-44-5]

TargetMol Chemicals

SAG dihydrochloride [2702366-44-5]

4

Chemical

Research Use Only

SAG dihydrochloride

C28H30Cl3N3OS

562.98

SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway. It also negates the effects of Cyclopamine inhibition on Smo.

3 years

O=C(C1=C(C2=CC=CC=C2S1)Cl)N([C@@H]3CC[C@H](CC3)NC)CC4=CC(C5=CC=NC=C5)=CC=C4.Cl.Cl

-20°C

12352200