Salvinorin A Carbamate [858345-57-0]

TargetMol Chemicals

Salvinorin A Carbamate [858345-57-0]

16

Chemical

Research Use Only

Salvinorin A Carbamate

C22H27NO8

433.457

Salvinorin A carbamate, a potent kappa-opioid receptor (KOR) full agonist, exhibits nearly the same potency as salvinorin A, with EC50 values of 6.2 and 4.5 nM, respectively, for activating the human KOR to augment the binding of [35S]GTPgammaS. Enhancing biological stability, the addition of a carbamate group to salvinorin A reduces deacetylation.

3 years

COC(=O)[C@@H]1C[C@H](OC(N)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1

-20°C

12352200