sappanone A

Selleck Chemicals

sappanone A [102067-84-5]

9

Research Use Only

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Sappanone A, a homoisoflavanone isolated from the heartwood of Caesalpinia sappan (Leguminosae), induces HO-1 expression by activating Nrf2 through the p38 MAPK pathway, suppresses LPS-induced NF-kappaB activation by suppressing the phosphorylation of RelA/p65 at Ser536, exerting its anti-inflammatory effect.

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