SAR502250 [503860-57-9]

MedChem Express

SAR502250 [503860-57-9]

10

503860-57-9

Research Use Only

99.63

C19H18FN5O2

367.38

SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3beta. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimers disease (AD)[1][2].

O=C1C=C(C2=NC=NC=C2)N=C(N3C[C@H](C4=CC=C(F)C=C4)OCC3)N1C

-20°C,2°C to 8°C

12131703