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[Sar9,Met(O2)11]-Substance P acetate

Name: [Sar9,Met(O2)11]-Substance P acetate
SKU: TP1369L_T03
Price: 3432 EUR
Availability: BackOrder

TP1369L

CAS NumberTP1369L

Product group Chemicals

Molecular Weight1467.75

Overview

Supplier
TargetMol Chemicals
Product Name
[Sar9,Met(O2)11]-Substance P acetate
Delivery Days Customer
9
CAS Number
TP1369L
Category Supplier
Chemical
Chemical Name
[Sar9,Met(O2)11]-Substance P acetate
Molecular Formula
C67H106N18O17S
Molecular Weight
1467.75
Scientific Description
[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P acetate is the sole to produce grooming.
Shelf life instruction
3 years
SMILES
O=C([C@H](CCCCN)NC([C@H]1N(C([C@@H](N)CCCNC(N)=N)=O)CCC1)=O)N(CCC2)[C@@H]2C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(N(C)CC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCS(C)(=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O.CC(O)=C.[O]
Storage Instruction
-20°
UNSPSC
12352200

Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.