SARS-CoV-2 3CLpro-IN-14

MedChem Express

SARS-CoV-2 3CLpro-IN-14

14

Research Use Only

C34H40F3N5O6S2

735.84

SARS-CoV-2 3CLpro-IN-14 (compound 11j) is an orally active SARS-CoV-2 3CLpro inhibitor. SARS-CoV-2 3CLpro-IN-14 shows significant anti- SARS-CoV-2 activity ( EC 50 = 0.18 microM) and low cytotoxicity ( CC 50 > 50 microM) in Vero E6 cells [1] .

FC(F)(F)S(=O)(N[C@H](C(N1[C@@H](C2)CC[C@@H]2[C@H]1C(N[C@H](C(C3=NC4=CC=CC=C4S3)=O)C[C@@H]5CCNC5=O)=O)=O)C6(C7)C[C@@H](C8)C[C@H]7C[C@@H]8C6)=O

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