SARS-CoV-2 3CLpro-IN-8

MedChem Express

SARS-CoV-2 3CLpro-IN-8

10

Research Use Only

C24H32FN3O5

461.53

SARS-CoV-2 3CLpro-IN-8, an aldehyde, is a broad-spectrum cyclopropane-based inhibitor of coronavirus 3C-like proteases (3CLpro). SARS-CoV-2 3CLpro-IN-8 inhibits SARS-CoV-2, SARS-CoV-1 and MERS-CoV 3CLpro with IC50 values of 80 nM, 180 nM, 960 nM, respectively. SARS-CoV-2 3CLpro-IN-8 inhibits SARS-CoV-2 replication with an IC50 value of 12 nM.

CC(C[C@@H](C(N[C@@H](C[C@H]1CCNC1=O)C=O)=O)NC(OC[C@@H]2C[C@H]2C3=CC=CC(F)=C3)=O)C

See Manual

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