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SARS-CoV-2-IN-10

T40340
TargetMol Chemicals
CAS Number2722634-95-7
Product group Chemicals
Molecular Weight521.606
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    SARS-CoV-2-IN-10
  • Delivery Days Customer
    999
  • CAS Number
    2722634-95-7
  • Category Supplier
    Chemical
  • Chemical Name
    SARS-CoV-2-IN-10
  • Molecular Formula
    C27H37F2N3O5
  • Molecular Weight
    521.606
  • Scientific Description
    SARS-CoV-2-IN-10 is a powerful and non-toxic inhibitor of SARS-CoV-2 3CL protease, with IC50 and EC50 values of 0.13 nM and 1.03 nM, respectively. The SARS-CoV-2 3C-like protease (3CLpro) is a critical enzyme for viral replication and serves as an ideal target for intervention. By targeting the SARS-CoV-2 3CL protease, SARS-CoV-2-IN-10 has the potential to facilitate the development of effective antiviral drugs specific to SARS-CoV-2.
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)C[C@H](NC(=O)OC(C1CCC(F)(F)CC1)c1ccccc1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C=O
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Dampalla CS, et al. Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, and Cell-Based Studies. J Med Chem. 2021;64(24):17846-17865.
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