SARS-CoV-2-IN-101

MedChem Express

SARS-CoV-2-IN-101

9

Research Use Only

C22H23N5O3

405.45

SARS-CoV-2-IN-101 (compound 10O) is a potent and orally active SARS-CoV-2 inhibitor with an EC50 value of 0.64 microM for HCoV-229E. SARS-CoV-2-IN-101 shows cyotoxicity. SARS-CoV-2-IN-101 decreases the expression of HCoV-229E N protein and RNA level. SARS-CoV-2-IN-101 shows broad-spectrum anti-coronaviral effect[1].

CN1C(N(C)C(N=C(NCCO)N2CC3=CC=C(C4=CC=CC=C4)C=C3)=C2C1=O)=O

12352200